Xcell™ Genomic Analytical Platform


The Xcell™ Genomic Analytical Platform combines next-generation sequencing (NGS) and advanced genomic analysis with deep expertise in bioinformatics and sample preparation. This comprehensive platform delivers tailored sequencing and bioinformatics solutions to address a wide range of scientific inquiries. We utilize complementary technologies such as PacBio and Nanopore for long reads, Illumina for short reads, and Bionano for optical mapping. In addition to our state-of-the-art equipment, we offer thorough sample preparation and technical support to ensure our clients receive the highest quality data and insights.

Our sequencing and bioinformatics services include:

Cell Line Genomic Characterization

NewBiologix has extensive expertise in cell line genomic characterization for cell and gene therapies. Our specialized staff utilize advanced instruments, including Illumina, PacBio and Bionano technology, to deliver rigorous quality control and tailored NGS sample preparation. Our robust genomic analytical platform delivers precise and reliable results, including raw sequencing data and a detailed report, in under 4 weeks for standard services (from sample receipt).

Table that shows the advantages of the New Biologix approach: scalability, consistent yield, reduced production costs, inducible rAAV production system, predictability/reproductibility, optimized packaging efficiency, full/empty capsid optimization

Applications

Regulatory
Clonality, integration site and transgene integrity
Stability &
Consistency
Monitoring genetic stability
Safety Assessment
Identifying potential off-target effects and integration sites
Cell Line Authentication
Verify identity and purity
Gene Editing Validation
Confirming successful modification of a gene
Pathway Analysis
Studying the effects of genetic changes
Stem Cell Research
Genomic changes and stability (Ploidy)

rAAV Genome Sequencing

Using PacBio technology for rAAV genome sequencing, NewBiologix offers a comprehensive and accurate method to analyze viral genomes, ensuring accurate characterization and high-quality control in the development of gene therapy products. 

Table that shows the advantages of the New Biologix approach: scalability, consistent yield, reduced production costs, inducible rAAV production system, predictability/reproductibility, optimized packaging efficiency, full/empty capsid optimization

Applications

Regulatory
Documentation for approval
Quality control
Consistency and stability
Safety Assessment
Detection of contaminants
Vector Efficacy
Gene of interest integrity
Vector Characterization
Detection of vector variants
Process development
Full/Empty capsid ratio optimization

Custom NGS Services

NewBiologix experts empower researchers with cutting-edge technology and expert support, delivering precise, high-quality genomic data tailored to your research needs, including comprehensive solutions from sample preparation to data analysis.

Contact us to get started on a custom NGS project.

Stable transfection rAAV/Ad genes

Our Available Technologies

device
Illumina NextSeq 2000
Technology
Short reads
Read length
Up to 2x300 bases
Target
Gene / transcript expression
SNVs detection
device
PacBio
Revio
Technology
Long reads
molecule length
From 150 to 20’000 bases
Target
Genome assembly
Complex genomic regions
Variant detection
Epigenetics
device
Nanopore MinION
Technology
Long reads
molecule length
Up to 4’000’000 bases
Target
Direct sequencing
Variant detection
Epigenetics
device
Bionano Saphyr
Technology
Optical genome mapping
molecule length
From 150’000 to 2’000'000 bases
Target
Alternative to karyotypes
Genome assembly validation
Structural variation detection

Our Team

With decades of expertise in next-generation sequencing and genomic data analysis, our team of highly skilled scientists and engineers offers you a comprehensive analysis, quality control, and interpretation of your submitted samples.

Learn More About Us

Scientists working in New Biologix labs.

Our values

Excellence

Accessibility

Curiosity

Genomic Analytical Platform Workflow

A diagram that explain the New Biologix workflow of Next-Generation Sequencing And Optical Mapping Platforms

NewBiologix is your Partner of Choice for NGS and Bioinformatics

Convenience and flexibility
Customized
Speed and reactivity
Confidentiality and data safety
Long-time data storage
Our technology provides a seamless extension of your capabilities and adapts to your program’s evolving needs. Partner with NewBiologix to unlock the full potential of your genomic research.
TECHNICAL EXPERTISE | TRANSPARENCY | FLEXIBILITY | PLATFORM-BASED SOLUTIONS